INT199576

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Raf1, Akt1) cytosol (Raf1, Akt1) signal transduction (Raf1, Akt1)
plasma membrane (Raf1, Akt1) kinase activity (Raf1, Akt1) transport (Akt1)
Raf1 (Mus musculus)
Akt1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 4 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Renal Cell Carcinoma 50 96.08 Very High Very High Very High
Adenocarcinoma 2 86.24 High High
Non-small-cell Lung Cancer 6 77.92 Quite High
Cancer 29 69.68 Quite High
Disease 31 62.20 Quite High
Gastrointestinal Stromal Tumor 2 58.16 Quite High
Myeloid Leukemia 2 55.20 Quite High
Disease Progression 3 44.04 Quite Low
Breast Cancer 2 30.12 Quite Low
Colon Cancer 2 27.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sorafenib is an orally administered bi-aryl urea that was designed originally as an inhibitor of BRAF and CRAF, non-receptor serine threonine kinases.
CRAF Negative_regulation (inhibitor) of kinases
1) Confidence 0.00 Published 2006 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661649 Disease Relevance 0.79 Pain Relevance 0

General Comments

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