INT199593

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.10
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.70
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TRPV1) transport (TRPV1) nucleus (Myoz1)
plasma membrane (TRPV1) lipid metabolic process (TRPV1)
Anatomy Link Frequency
nerve 1
TRPV1 (Homo sapiens)
Myoz1 (Mus musculus)
Pain Link Frequency Relevance Heat
unmyelinated 2 100.00 Very High Very High Very High
qutenza 8 99.80 Very High Very High Very High
cytokine 4 95.28 Very High Very High Very High
Central nervous system 2 95.12 Very High Very High Very High
Inflammation 2 90.24 High High
pruritus 84 87.20 High High
burning pain 2 84.16 Quite High
Cannabinoid receptor 2 82.60 Quite High
Opioid 2 81.52 Quite High
Neuropeptide 4 80.88 Quite High
Disease Link Frequency Relevance Heat
Nociception 4 93.40 High High
INFLAMMATION 2 90.24 High High
Pruritus 168 89.64 High High
Eczema 16 86.24 High High
Pain 2 84.16 Quite High
Disease 14 82.64 Quite High
Biliary Liver Cirrhosis 2 39.76 Quite Low
Uremia 6 32.40 Quite Low
Dermatological Disease 4 5.00 Very Low Very Low Very Low
Acne 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In current studies there is indirect evidence that next to capsaicin also the calcineurin inhibitors may bind to the TRPV1 (Ständer, Steinhoff, Ständer, et al 2003; Senba et al 2004).
TRPV1 Binding (bind) of calcineurin associated with qutenza
1) Confidence 0.10 Published 2006 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661653 Disease Relevance 1.04 Pain Relevance 0.61
Furthermore, recent investigations suggest that calcineurin inhibitors may also directly influence nerve fiber function by possible binding to a receptor on small, unmyelinated sensory nerve fibers, the TRPV1 (VR1, capsaicin receptor) (Ständer, Steinhoff, Ständer, et al 2003; Senba et al 2004).
TRPV1 Binding (binding) of calcineurin in nerve associated with qutenza and unmyelinated
2) Confidence 0.07 Published 2006 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661653 Disease Relevance 0.66 Pain Relevance 0.63

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox