INT199598

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Context Info
Confidence 0.48
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 2.83
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (FGF7) extracellular space (FGF7) extracellular region (FGF7)
Golgi apparatus (FGF7)
FGF7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 37 90.48 High High
cytokine 33 90.48 High High
Analgesic 5 71.40 Quite High
Piles 2 64.20 Quite High
Pain 11 5.00 Very Low Very Low Very Low
methotrexate 9 5.00 Very Low Very Low Very Low
cryotherapy 4 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
analgesia 3 5.00 Very Low Very Low Very Low
palliative 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 48 96.84 Very High Very High Very High
Cancer 185 96.52 Very High Very High Very High
Mucositis 163 94.64 High High
INFLAMMATION 37 90.48 High High
Wound Healing 2 79.92 Quite High
Anorectal Disorders 2 64.20 Quite High
Apoptosis 14 63.04 Quite High
Stomatitis 59 50.00 Quite Low
Adhesions 4 46.80 Quite Low
Malignant Neoplastic Disease 10 38.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of KGF is mediated by binding to the KGF receptor, which, in normal cells, binds KGF with high affinity.
KGF receptor Binding (binds) of
1) Confidence 0.48 Published 2010 Journal Radiat Environ Biophys Section Body Doc Link PMC2855434 Disease Relevance 0.45 Pain Relevance 0
When bound to the receptor, KGF is internalized by endocytosis (MacDonald and Hill 2002).
KGF Binding (bound) of
2) Confidence 0.40 Published 2006 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661654 Disease Relevance 0.22 Pain Relevance 0.09
The effect of KGF is mediated by binding to the KGF receptor, which, in normal cells, binds KGF with high affinity.
KGF Binding (binds) of
3) Confidence 0.31 Published 2010 Journal Radiat Environ Biophys Section Body Doc Link PMC2855434 Disease Relevance 0.40 Pain Relevance 0
Still, Palifermin

(recombinant human KGF-1) remains the only agent currently approved by the FDA for

KGF-1 Binding (recombinant) of
4) Confidence 0.02 Published 2008 Journal Journal of Oncology Section Body Doc Link PMC2648637 Disease Relevance 0.88 Pain Relevance 0.41
Still, Palifermin

(recombinant human KGF-1) remains the only agent currently approved by the FDA for

KGF-1 Binding (agent) of
5) Confidence 0.02 Published 2008 Journal Journal of Oncology Section Body Doc Link PMC2648637 Disease Relevance 0.87 Pain Relevance 0.40

General Comments

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