INT199785

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Context Info
Confidence 0.15
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.60
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Ppig) protein folding (Ppig) nucleus (Ppig)
cytoplasm (Ppig)
Ppig (Mus musculus)
Pain Link Frequency Relevance Heat
Taxol 2 60.08 Quite High
antidepressant 3 54.08 Quite High
Bile 39 7.92 Low Low
Inflammation 17 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Crohn's disease 6 5.00 Very Low Very Low Very Low
Versed 3 5.00 Very Low Very Low Very Low
Nicotine 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 68 92.88 High High
Cancer 19 89.72 High High
Pulmonary Disease 3 54.08 Quite High
Asthma 2 51.64 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 49.84 Quite Low
Lung Cancer 7 42.72 Quite Low
Inflammatory Bowel Disease 32 5.00 Very Low Very Low Very Low
Targeted Disruption 17 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Disease 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Likewise, changes in the expression of CYP transcripts may influence an individual’s capacity to convert different precarcinogenic compounds into their ultimate carcinogens; therefore, these CYP transcripts are of major importance for an individual’s susceptibility of developing chemically induced cancer.
Transcription (expression) of CYP associated with cancer
1) Confidence 0.15 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1665420 Disease Relevance 0.60 Pain Relevance 0
Second, SXR activation directly stimulates the transcription of CYP enzymes in response to the presence of its ligands and plays a central role in the transcriptional regulation of CYP3A4.
Transcription (transcription) of CYP
2) Confidence 0.03 Published 2009 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2646121 Disease Relevance 0 Pain Relevance 0.06

General Comments

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