INT199798

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 7
Disease Relevance 5.85
Pain Relevance 2.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (BBS2) cytoplasm (BBS2)
Anatomy Link Frequency
heart 1
BBS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
beta blocker 492 100.00 Very High Very High Very High
Angina 12 83.48 Quite High
tolerance 6 69.76 Quite High
Calcium channel 6 25.12 Quite Low
agonist 42 5.00 Very Low Very Low Very Low
Nicotine 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 369 99.78 Very High Very High Very High
Nicotine Addiction 68 99.08 Very High Very High Very High
Coronary Artery Disease 36 98.56 Very High Very High Very High
Myocardial Infarction 66 98.40 Very High Very High Very High
Diabetes Mellitus 18 95.92 Very High Very High Very High
Increased Venous Pressure Under Development 12 94.76 High High
Phobia 18 88.40 High High
Bronchospasm 30 87.76 High High
Lung Cancer 6 87.60 High High
Disease 31 87.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We suggest that patients who are admitted with any cardiac condition requiring BBs and who have concomitant COPD should be tried on BBs.
Positive_regulation (requiring) of BBs associated with pulmonary disease and beta blocker
1) Confidence 0.50 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699954 Disease Relevance 0.60 Pain Relevance 0.51
They recommend that BBs are initiated at a low dose and uptitrated gradually in two weeks intervals.
Positive_regulation (initiated) of BBs associated with beta blocker
2) Confidence 0.42 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699954 Disease Relevance 0.45 Pain Relevance 0.38
We suggest that patients who are admitted with any cardiac condition requiring BBs and who have concomitant COPD should be tried on BBs.
Positive_regulation (tried) of BBs associated with pulmonary disease and beta blocker
3) Confidence 0.36 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699954 Disease Relevance 0.60 Pain Relevance 0.51
Many patients with COPD have concomitant conditions such as CAD (coexists in up to 27% of COPD patients (Karoli and Rebrov 2005)) that require the use of BBs.
Positive_regulation (require) of BBs associated with coronary artery disease, pulmonary disease and beta blocker
4) Confidence 0.36 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699954 Disease Relevance 1.44 Pain Relevance 0.45
A short acting cardioselective BBs (such as metoprolol) should be started at a low dose and uptitrated slowly.
Positive_regulation (uptitrated) of BBs associated with beta blocker
5) Confidence 0.36 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699954 Disease Relevance 0.76 Pain Relevance 0.40
For instance, BBs are well tolerated by the large majority of patients with heart failure, even in those with comorbid conditions such as diabetes mellitus, COPD, and peripheral vascular disease (HFSA 2006).
Positive_regulation (tolerated) of BBs in heart associated with pulmonary disease, beta blocker, diabetes mellitus, increased venous pressure under development and myocardial infarction
6) Confidence 0.36 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699954 Disease Relevance 0.99 Pain Relevance 0.31
We also observed induction of the carcinogen-metabolizing enzymes GSTP1 in BAL cells and BBs and GSTA2 in BBs from smokers.
Positive_regulation (enzymes) of BBs associated with nicotine addiction
7) Confidence 0.04 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1665420 Disease Relevance 1.01 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox