INT199851

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.04
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Casp8) peptidase activity (Casp8) mitochondrion (Casp8)
nucleus (Casp8) protein complex (Casp8) cytoplasm (Casp8)
Anatomy Link Frequency
Cleavage 2
Casp8 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 1 87.92 High High
palliative 1 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 60 98.16 Very High Very High Very High
Death 14 92.28 High High
Non-small-cell Lung Cancer 16 50.00 Quite Low
Lung Cancer 10 9.28 Low Low
Cancer 46 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 4 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Osteogenic Sarcomas 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cleavage of caspase-8 and Bid was low in KNS62 cells after GEM and PB treatment alone, but significantly increased with combination therapy (Fig. 3a).
Positive_regulation (increased) of Protein_catabolism (Cleavage) of caspase-8 in Cleavage
1) Confidence 0.07 Published 2006 Journal J Carcinog Section Body Doc Link PMC1665446 Disease Relevance 1.04 Pain Relevance 0.04

General Comments

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