INT199860

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Gopc, Mapk8) mitochondrion (Mapk8) transport (Gopc)
Golgi apparatus (Gopc) cytosol (Mapk8) signal transduction (Mapk8)
Gopc (Mus musculus)
Mapk8 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 1 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 60 98.22 Very High Very High Very High
Non-small-cell Lung Cancer 16 97.68 Very High Very High Very High
Cancer 46 97.20 Very High Very High Very High
Severe Combined Immunodeficiency 4 96.40 Very High Very High Very High
Death 14 5.00 Very Low Very Low Very Low
Lung Cancer 10 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Osteogenic Sarcomas 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Only specific blocking of p-JNK significantly inhibited the induction of apoptosis by chemotherapy (Figure 5b), whereas the level of phosphorylated c-Jun as the target of activated JNK was effectively decreased by the JNK inhibitor SP600125 (Fig. 5c).


Fig Negative_regulation (decreased) of Positive_regulation (activated) of JNK associated with apoptosis
1) Confidence 0.07 Published 2006 Journal J Carcinog Section Body Doc Link PMC1665446 Disease Relevance 1.07 Pain Relevance 0

General Comments

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