INT199970

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CYP19A1, ESR1) nucleoplasm (ESR1) small molecule metabolic process (CYP19A1)
endoplasmic reticulum (CYP19A1) enzyme binding (ESR1) DNA binding (ESR1)
Anatomy Link Frequency
endometrium 2
CYP19A1 (Homo sapiens)
ESR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 18 97.64 Very High Very High Very High
antagonist 3 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis (extended) 18 97.64 Very High Very High Very High
Reprotox - General 3 6 77.48 Quite High
Breast Cancer 1 76.24 Quite High
Polycystic Ovary Syndrome 9 74.88 Quite High
Hypersensitivity 1 27.84 Quite Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Endometrial Cancer 1 5.00 Very Low Very Low Very Low
Hypertrophy 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
If aromatase increases local estrogen production within the endometrium, this might alter the balance between estrogen and progesterone and could therefore account for the elevation in ER-alpha observed in this study.
aromatase Positive_regulation (increases) of Gene_expression (production) of estrogen in endometrium
1) Confidence 0.06 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1679803 Disease Relevance 0.72 Pain Relevance 0.25

General Comments

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