INT199987

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (DBT) small molecule metabolic process (DBT) transferase activity, transferring acyl groups (DBT)
cellular nitrogen compound metabolic process (DBT) cytoplasm (DBT)
Anatomy Link Frequency
endometrium 2
DBT (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 1 36.72 Quite Low
endometriosis 18 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Togavirus Infection 123 66.48 Quite High
Endometriosis (extended) 18 5.00 Very Low Very Low Very Low
Polycystic Ovary Syndrome 9 5.00 Very Low Very Low Very Low
Reprotox - General 3 6 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Hepatitis A Virus Infection 2 5.00 Very Low Very Low Very Low
Viral Meningitis 2 5.00 Very Low Very Low Very Low
Measles 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Blocking with two E2-specific, non-neutralizing MAbs (F2 and H6) did not have the desired effect of increasing the isolation of neutralizing Fabs; instead this blocking seemed to have inhibited binding of E2-specific Fabs since only E1-specific Fabs were isolated.
Negative_regulation (inhibited) of E2 Spec (seemed) Binding (binding) of
1) Confidence 0.04 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2903468 Disease Relevance 0.07 Pain Relevance 0
While progesterone is an effective anti-estrogen, its role is to reduce ER-alpha concentration rather than to act as a competetive inhibitor of E2 binding, thereby rendering the endometrium resistant to estrogen during the window of implantation.
Negative_regulation (inhibitor) of E2 Binding (binding) of in endometrium
2) Confidence 0.03 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1679803 Disease Relevance 0 Pain Relevance 0

General Comments

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