INT200211

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Context Info
Confidence 0.38
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Gh, Igf1) extracellular region (Gh, Igf1) cytosol (Gh)
signal transduction (Gh) mitochondrion (Gh) plasma membrane (Gh)
Anatomy Link Frequency
liver 4
Gh (Mus musculus)
Igf1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 6 98.88 Very High Very High Very High
Syndrome 34 91.76 High High
Body Weight 20 91.44 High High
Hypoglycemia 12 87.60 High High
Hypothermia 2 87.04 High High
Lifespan 28 85.72 High High
Disease 12 66.40 Quite High
Dwarfism 50 57.48 Quite High
Death 26 52.80 Quite High
Hutchinson-gilford Progeria Syndrome 82 52.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GH mediates its effects largely through the increased secretion of insulin-like growth factor 1 (IGF-1) in target tissues including the liver.
GH Positive_regulation (mediates) of Localization (secretion) of insulin-like growth factor 1 in liver
1) Confidence 0.38 Published 2006 Journal PLoS Genetics Section Body Doc Link PMC1698946 Disease Relevance 1.02 Pain Relevance 0
GH mediates its effects largely through the increased secretion of insulin-like growth factor 1 (IGF-1) in target tissues including the liver.
GH Positive_regulation (mediates) of Localization (secretion) of IGF-1 in liver
2) Confidence 0.28 Published 2006 Journal PLoS Genetics Section Body Doc Link PMC1698946 Disease Relevance 1.02 Pain Relevance 0

General Comments

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