INT200311

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Context Info
Confidence 0.05
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Htt, Rest) cytoplasm (Htt, Rest) cytosol (Htt, Rest)
nucleus (Htt, Rest) transcription factor binding (Htt, Rest) Golgi apparatus (Htt)
Anatomy Link Frequency
nucleus 1
Htt (Mus musculus)
Rest (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 80 52.88 Quite High
Central nervous system 1 19.52 Low Low
Morphine 3 5.00 Very Low Very Low Very Low
opioid receptor 3 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 99.30 Very High Very High Very High
Repression 14 98.52 Very High Very High Very High
Neurodegenerative Disease 1 71.72 Quite High
Targeted Disruption 2 68.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In Huntington's disease, it has been proposed that mutant huntingtin led to accumulate the NRSF in nucleus, resulting in the strong repression of the BDNF which is controlled by NRSE (39).
huntingtin Positive_regulation (accumulate) of NRSF in nucleus associated with repression and disease
1) Confidence 0.05 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1702488 Disease Relevance 0.75 Pain Relevance 0.03

General Comments

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