INT200353

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.31
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Rest) DNA binding (Rest) protein complex (Rest)
signal transducer activity (Oprm1) cytoplasm (Rest) cytosol (Rest)
Anatomy Link Frequency
neuronal 1
Rest (Mus musculus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 80 100.00 Very High Very High Very High
Morphine 3 5.00 Very Low Very Low Very Low
opioid receptor 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 14 98.56 Very High Very High Very High
Disease 4 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene

Previously, we reported that the neuron-restrictive silencer element (NRSE) of mu opioid receptor (MOR) functions as a critical regulator to repress the MOR transcription in specific neuronal cells, depending on neuron-restriction silence factor (NRSF) expression levels [C.S.Kim, C.K.Hwang, H.S.Choi, K.Y.Song, P.Y.Law, L.N.Wei and H.H.Loh (2004) J.

neuron-restrictive silencer element Negative_regulation (repress) of MOR in neuronal associated with repression and mu opioid receptor
1) Confidence 0.31 Published 2006 Journal Nucleic Acids Research Section Title Doc Link PMC1702488 Disease Relevance 0.10 Pain Relevance 0.39

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox