INT200441

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Context Info
Confidence 0.36
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (AES)
AES (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 27 45.76 Quite Low
Arthritis 9 5.00 Very Low Very Low Very Low
Infliximab 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Etanercept 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthropathy 97 99.98 Very High Very High Very High
Carcinoma 5 86.04 High High
Overactive Bladder 3 84.72 Quite High
Disease 12 71.56 Quite High
Lower Urinary Tract Symptoms 1 69.68 Quite High
Bladder Cancer 10 50.00 Quite Low
Psoriasis 29 45.76 Quite Low
Recurrence 6 29.64 Quite Low
Infection 1 14.08 Low Low
Toxicity 16 10.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Arthropathy AEs appeared to be less likely to occur in patients who had a good clinical response to treatment (?
Spec (likely) Negative_regulation (less) of Spec (likely) Gene_expression (likely) of AEs associated with arthropathy
1) Confidence 0.36 Published 2006 Journal Arch Dermatol Res Section Body Doc Link PMC1705535 Disease Relevance 1.26 Pain Relevance 0
It is also interesting to note that failure to reach an MTD for VB4-845 over the dose range tested and the apparent absence of any relationship between the appearance of AEs and dose are in keeping with its excellent safety profile.
Negative_regulation (absence) of Gene_expression (appearance) of AEs
2) Confidence 0.04 Published 2010 Journal Drug Design, Development and Therapy Section Body Doc Link PMC2998804 Disease Relevance 0.30 Pain Relevance 0

General Comments

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