INT200602

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.21
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itga2b)
Anatomy Link Frequency
platelets 4
Itga2b (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 10 68.88 Quite High
cytokine 6 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 16 91.92 High High
Thrombosis 68 85.76 High High
Hypothermia 92 82.96 Quite High
Endotoxemia 42 66.76 Quite High
Sepsis 32 55.20 Quite High
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Fever 4 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 4 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of interest, spontaneous platelet GPIIb-IIIa expression did not increase but even slightly decreased after endotoxin exposure, and thrombin-stimulation of endotoxin-exposed platelets also induced an only slight but not significant elevation of expression.
Neg (not) Positive_regulation (increase) of Gene_expression (expression) of GPIIb-IIIa in platelets
1) Confidence 0.04 Published 2006 Journal Crit Care Section Body Doc Link PMC1751084 Disease Relevance 0.88 Pain Relevance 0.07
In platelets of saline controls (37°C), in vitro stimulation with thrombin resulted in elevated expression of P-selectin, GPIIb-IIIa and CD107a.
Positive_regulation (elevated) of Gene_expression (expression) of GPIIb-IIIa in platelets
2) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1751084 Disease Relevance 0.33 Pain Relevance 0

General Comments

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