INT200608

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.03
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itga2b)
Anatomy Link Frequency
platelet 4
Itga2b (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 10 57.84 Quite High
cytokine 6 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypothermia 92 99.72 Very High Very High Very High
Thrombosis 68 94.52 High High
Endotoxemia 42 93.48 High High
Adhesions 16 80.88 Quite High
Sepsis 32 76.48 Quite High
Increased Venous Pressure Under Development 2 10.24 Low Low
Coronary Artery Disease 2 6.32 Low Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Fever 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because concomitant systemic hypothermia also did not affect GPIIb-IIIa expression, our data suggest that platelet expression of this molecule did not substantively contribute to low temperature-induced acceleration of thrombus formation during endotoxemia.
Neg (not) Regulation (affect) of Gene_expression (expression) of GPIIb-IIIa in platelet associated with endotoxemia, hypothermia and thrombosis
1) Confidence 0.04 Published 2006 Journal Crit Care Section Body Doc Link PMC1751084 Disease Relevance 0.84 Pain Relevance 0.05
However, hypothermic incubation of the LPS-exposed platelets at 34°C and 31°C did not further affect the P-selectin, GPIIb-IIIa and CD107a expression (data not shown).


Neg (not) Regulation (affect) of Gene_expression (expression) of GPIIb-IIIa in platelets
2) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1751084 Disease Relevance 0.18 Pain Relevance 0

General Comments

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