INT200678

Context Info Confidence 0.47 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.57 Pain Relevance 0

nucleoplasm (AKT2) transport (AKT2) mitochondrion (AKT2) carbohydrate metabolic process (AKT2) cytoplasm (AKT2) cytosol (AKT2)

AKT2 (Homo sapiens)

Pain Link Frequency Relevance Heat Migraine 1 5.00 withdrawal 1 5.00 headache 1 5.00

Disease Link Frequency Relevance Heat Death 25 74.16 Apoptosis 41 73.92 Repression 2 68.92 Cancer 26 65.36 Malignant Neoplastic Disease 2 51.40 Cervical Cancer 5 26.32 Ovarian Cancer 2 5.00 Epilepsy 1 5.00 Headache 1 5.00 Cluster Headache 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It appears that these inhibitors repress Akt1 and Akt2 transcription thereby depleting the cellular Akt protein.

Transcription (transcription) of Akt2

1) Confidence 0.47 Published 2006 Journal Mol Cancer Section Body Doc Link PMC1762018 Disease Relevance 0.57 Pain Relevance 0

General Comments

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