INT200759

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Context Info
Confidence 0.21
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.88
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Rpe) carbohydrate metabolic process (Rpe)
Anatomy Link Frequency
retina 2
INL 2
Rpe (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 9 58.00 Quite High
Central nervous system 4 5.00 Very Low Very Low Very Low
bDMF 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fatigue 85 99.32 Very High Very High Very High
Cytomegalovirus Infection 32 95.00 High High
Ganglion Cysts 14 65.92 Quite High
Retinal Diseases 12 64.00 Quite High
INFLAMMATION 11 58.00 Quite High
Respiratory Syncytial Virus 13 52.32 Quite High
Muscular Dystrophy 11 47.28 Quite Low
Disease 17 44.72 Quite Low
Muscle Disease 1 39.28 Quite Low
Eye Disease 4 37.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RPE scores after FT were used for statistical comparisons between conditions

Tracking performance

Positive_regulation (used) of Gene_expression (scores) of RPE
1) Confidence 0.21 Published 2007 Journal Exp Brain Res Section Body Doc Link PMC1914220 Disease Relevance 0.41 Pain Relevance 0
The purity of RPE cells was evaluated by the expression of CRALBP (a marker for RPE cells and Müller cells) and RPE-65 (a marker for RPE cells) using specific antibodies.


Positive_regulation (evaluated) of Gene_expression (expression) of RPE
2) Confidence 0.13 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2642846 Disease Relevance 0 Pain Relevance 0
Greater than 95% of cells were positive for RPE-65 protein expression.
Positive_regulation (positive) of Gene_expression (expression) of RPE
3) Confidence 0.12 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2642846 Disease Relevance 0 Pain Relevance 0
Four weeks after subretinal injection, we observed intense eGFP expression in young and adult groups in the RPE, ONL, INL, OPL, IPL, RGC layers, and Müller cells (Figure 2B,C).
Positive_regulation (intense) of Gene_expression (groups) of RPE in INL
4) Confidence 0.10 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2713732 Disease Relevance 0.41 Pain Relevance 0
Subretinal injection of both types of nanoparticles resulted in substantial transfection of the retina and RPE.
Positive_regulation (transfection) of Gene_expression (transfection) of RPE in retina
5) Confidence 0.06 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762345 Disease Relevance 0.06 Pain Relevance 0.03

General Comments

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