INT200804

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Context Info
Confidence 0.38
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Gab2) intracellular (Gab2) protein complex (Gab2)
cytoplasm (Gab2)
Anatomy Link Frequency
spleens 2
Gab2 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 1 26.28 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Parenteral administration 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Erythrocytosis 35 50.00 Quite Low
Myeloid Leukemia 9 37.04 Quite Low
Myelofibrosis 18 32.96 Quite Low
Hyperplasia 1 28.32 Quite Low
Hemorrhage 10 26.28 Quite Low
Sprains And Strains 13 21.36 Low Low
Splenomegaly 3 17.00 Low Low
Anaemia 1 8.08 Low Low
Myelodysplastic Syndromes 62 5.00 Very Low Very Low Very Low
Congenital Anomalies 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was increased phosphorylation of Gab2 and ERK in spleens and BM from JAK2 V617F recipients that were somewhat variable from sample to sample, but no consistent activation of Akt (data not shown).
Positive_regulation (increased) of Phosphorylation (phosphorylation) of Gab2 in spleens
1) Confidence 0.38 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762384 Disease Relevance 0 Pain Relevance 0

General Comments

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