INT200806

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Context Info
Confidence 0.39
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 4.24
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
germline 1
CFU-E 1
EEC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 73 100.00 Very High Very High Very High
Inflammation 21 69.04 Quite High
cva 4 59.44 Quite High
alcohol 5 39.48 Quite Low
Piles 5 37.12 Quite Low
Eae 15 5.00 Very Low Very Low Very Low
Spinal cord 5 5.00 Very Low Very Low Very Low
Dismenorea 5 5.00 Very Low Very Low Very Low
depression 5 5.00 Very Low Very Low Very Low
withdrawal 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Epispadias 85 99.98 Very High Very High Very High
Cyst 7 99.54 Very High Very High Very High
Stress Incontinence 185 98.80 Very High Very High Very High
Congenital Anomalies 70 98.28 Very High Very High Very High
Aneuploidy 5 97.98 Very High Very High Very High
Disease 34 97.88 Very High Very High Very High
Spontaneous Abortion 10 94.88 High High
Down Syndrome 5 94.88 High High
Bladder Exstrophy 220 94.24 High High
Chromosome Aberrations 5 85.32 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All sections of the EEC have a specific clinical presentation and are obviously recognized right after birth by the pediatrician and the obstetrician.


EEC Binding (recognized) of
1) Confidence 0.39 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2777855 Disease Relevance 0.72 Pain Relevance 0.07
Aneuploidy of sex chromosomes in five of these cases might point to (a) gonosomal loci (locus) involved in the formation of EEC.
EEC Spec (might) Binding (formation) of associated with aneuploidy
2) Confidence 0.39 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2777855 Disease Relevance 0.64 Pain Relevance 0
MRI imaging in EEC
EEC Binding (imaging) of associated with imagery
3) Confidence 0.30 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2777855 Disease Relevance 0.28 Pain Relevance 0.19
Exstrophy-epispadias complex (EEC), refers to the whole spectrum
EEC Binding (complex) of associated with epispadias
4) Confidence 0.30 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2777855 Disease Relevance 0.81 Pain Relevance 0
As for other birth defects, a small subgroup of cases may follow Mendelian inheritance whereas in the majority, EEC is inherited as a complex trait with multiple genetic factors (heritable or de novo somatic or germline mutations), and complex gene-gene, or gene-environment interactions contributing to its formation.


EEC Binding (interactions) of in germline associated with congenital anomalies
5) Confidence 0.29 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2777855 Disease Relevance 0.37 Pain Relevance 0
The mastoid antrum was entered and the cyst was excised along its direction to the EEC.
EEC Binding (direction) of associated with cyst
6) Confidence 0.09 Published 2010 Journal BMC Ear Nose Throat Disord Section Body Doc Link PMC2853487 Disease Relevance 0.67 Pain Relevance 0.03
CFU-E from BM or spleen of these recipients showed increased sensitivity to Epo, with about 25–30% of CFU-E growing in the absence of exogenous Epo (Figure 1H), demonstrating the presence of EEC in the polycythemic mice.
EEC Binding (presence) of in CFU-E
7) Confidence 0.03 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762384 Disease Relevance 0.75 Pain Relevance 0

General Comments

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