INT200821

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Context Info
Confidence 0.14
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Jak2, Mvd) kinase activity (Jak2, Mvd) cell differentiation (Jak2)
lyase activity (Mvd) histone binding (Jak2) peroxisome (Mvd)
Jak2 (Mus musculus)
Mvd (Mus musculus)
Jak2 - V617F (1)
Pain Link Frequency Relevance Heat
Bioavailability 1 75.60 Quite High
cytokine 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Parenteral administration 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 9 97.56 Very High Very High Very High
Congenital Anomalies 10 94.44 High High
Myelofibrosis 18 93.28 High High
Erythrocytosis 35 92.04 High High
Myelodysplastic Syndromes 62 64.64 Quite High
Myeloid Leukemia 9 64.36 Quite High
Reticulocytosis 5 38.72 Quite Low
Sprains And Strains 13 5.00 Very Low Very Low Very Low
Hemorrhage 10 5.00 Very Low Very Low Very Low
Leukocytosis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further studies using this model should clarify the molecular pathogenesis of JAK2 V617F-associated MPD, and allow preclinical testing of novel therapies for these diseases.



JAK2 V617F (V617F) Binding (associated) of MPD associated with disease
1) Confidence 0.14 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762384 Disease Relevance 0.68 Pain Relevance 0.04

General Comments

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