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Context Info
Confidence 0.23
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.94
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Kit) cell differentiation (Kit) extracellular space (Kit)
plasma membrane (Kit) nucleus (Kit) kinase activity (Kit)
Anatomy Link Frequency
platelet 2
Kit (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 63.36 Quite High
Central nervous system 7 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 11 93.40 High High
Myeloid Leukemia 85 88.88 High High
Solid Tumor 1 71.52 Quite High
Overdose 1 62.80 Quite High
Teratoma 10 60.36 Quite High
Blast Crisis 4 58.92 Quite High
Recurrence 6 55.80 Quite High
Leukemia 15 50.00 Quite Low
Severe Combined Immunodeficiency 2 50.00 Quite Low
Toxicity 6 23.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cells were then trypsinized for 1 minute, centrifuged, washed with PBS, fixed in 4% paraformaldehyde for 0.5 hour at room temperature, washed and blocked in 2%FCS for 0.5 hour at room temperature with agitation. 1.5×105cells were then incubated with each of the following conjugated monoclonal antibodies: Tie-2, Flk-1, CD34, c-Kit, Thy-1, Sca-1 (PharMingen, San Diego, CA) for 90 mins at room temperature.
Negative_regulation (blocked) of c-Kit Binding (temperature) of
1) Confidence 0.23 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762397 Disease Relevance 0.30 Pain Relevance 0.06
These compounds also inhibit Bcr-Abl, Kit and platelet-derived growth factor receptor ?
Negative_regulation (inhibit) of Kit Binding (compounds) of in platelet
2) Confidence 0.13 Published 2009 Journal OncoTargets and therapy Section Body Doc Link PMC2886328 Disease Relevance 0.64 Pain Relevance 0

General Comments

This test has worked.

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