INT200897

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gria1) endoplasmic reticulum (Gria1) plasma membrane (Gria1)
protein complex (Gria1)
Anatomy Link Frequency
neurons 2
Gria1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nMDA receptor 18 98.98 Very High Very High Very High
agonist 6 97.66 Very High Very High Very High
Dopamine 113 65.96 Quite High
depression 19 50.00 Quite Low
cocaine 1 46.32 Quite Low
Hippocampus 9 5.00 Very Low Very Low Very Low
dopamine receptor 7 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
long-term potentiation 4 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 19 50.00 Quite Low
Schizophrenia 3 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another study employed dihydrexidine (D1/5 agonist) stimulation of cultured hippocampal neurons while NMDA receptors were blocked with APV, and found that the surface GluR1 immunoreactivity and colocalization with synaptophysin was reduced, and the mEPSC frequency was inhibited [27], thus exhibiting a cellular outcome for this ambiguous form of transactivation between these two types of receptors.
Negative_regulation (reduced) of Localization (colocalization) of GluR1 in neurons associated with nmda receptor and agonist
1) Confidence 0.07 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762427 Disease Relevance 0 Pain Relevance 0.22

General Comments

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