INT200953

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Context Info
Confidence 0.30
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

CALM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cannabis 16 99.40 Very High Very High Very High
cocaine 28 99.20 Very High Very High Very High
drug abuse 57 88.16 High High
addiction 3 48.16 Quite Low
alcohol 4 5.00 Very Low Very Low Very Low
Opioid 3 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Nucleus accumbens 2 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 3 95.16 Very High Very High Very High
Obesity 4 91.84 High High
Cardiovascular Disease 9 90.68 High High
Drug Dependence 58 88.16 High High
Disorder Of Lipid Metabolism 5 85.00 Quite High
Phencyclidine Abuse 4 61.20 Quite High
Death 4 5.00 Very Low Very Low Very Low
Overweight 4 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, humans who abused cocaine, cannabis and/or phencyclidine share a decrease in transcription of calmodulin-related genes and increased transcription related to lipid/cholesterol and Golgi/ER function.
Negative_regulation (decrease) of Transcription (transcription) of calmodulin associated with cannabis and cocaine
1) Confidence 0.30 Published 2006 Journal PLoS ONE Section Abstract Doc Link PMC1762434 Disease Relevance 0.64 Pain Relevance 0.34

General Comments

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