INT201028

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Context Info
Confidence 0.71
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (TGFBI) extracellular space (TGFBI) extracellular region (TGFBI)
plasma membrane (TGFBI) extracellular matrix organization (TGFBI)
Anatomy Link Frequency
tear 1
extracellular matrix 1
internal 1
TGFBI (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 3 17.00 Low Low
eye pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 1 100.00 Very High Very High Very High
Hereditary Corneal Dystrophies 1 94.20 High High
Adenocarcinoma 1 75.08 Quite High
Disorders Of The Lacrimal System 17 74.88 Quite High
Disease 13 46.72 Quite Low
Amyloidosis 2 36.80 Quite Low
Photophobia 1 17.52 Low Low
Pain 3 17.00 Low Low
Pruritus 4 5.00 Very Low Very Low Very Low
Eye Pain 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The TGFBI gene product is a secreted protein of 683 amino acids, consisting of four regions of internal homology of approximately 140 amino acids and a carboxy terminal Arg-Gly-Asp (RGD) sequence.
Localization (secreted) of TGFBI in internal
1) Confidence 0.71 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2786890 Disease Relevance 0.17 Pain Relevance 0
Predominantly expressed by the corneal epithelium, TGFBI is believed to be an adhesion protein secreted into the extracellular matrix and bound to Type I, II, and IV collagens responsible for the structure of microfibrils and cell surface.
Localization (secreted) of TGFBI in extracellular matrix associated with adhesions
2) Confidence 0.67 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2822555 Disease Relevance 0.10 Pain Relevance 0
Many workers complained about eye discomfort, and therefore we conducted a study to evaluate the tear secretion function of light-on test workers of a TFT-LCD company.


Localization (secretion) of TFT-LCD in tear
3) Confidence 0.52 Published 2006 Journal BMC Public Health Section Abstract Doc Link PMC1764015 Disease Relevance 0.07 Pain Relevance 0

General Comments

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