INT201041

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Context Info
Confidence 0.32
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.10
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CAPN7) nucleus (CAPN7) intracellular (CAPN7)
Anatomy Link Frequency
crops 1
internal 1
CAPN7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 2 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Invasive Pulmonary Aspergillosis 100 98.84 Very High Very High Very High
Pneumonia 18 91.48 High High
Disease 12 87.60 High High
Infection 19 63.28 Quite High
Aspergillus Infection 18 59.24 Quite High
Sprains And Strains 5 55.92 Quite High
Fungal Infection 14 55.44 Quite High
Cancer 14 53.32 Quite High
Death 3 52.36 Quite High
Hepatocellular Cancer 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We developed a qPCR approach for the diagnosis of IPA that incorporates rigorous quality control steps designed to determine if fungal contamination is introduced at the DNA extraction or PCR set up stages, if human DNA is present in the extracted samples and at what level (extraction control), if PCR inhibitors are present after DNA extraction and to what extent they cause inhibition (internal amplification control), and if large amounts of human genomic DNA impede the Aspergillus qPCR.
Negative_regulation (impede) of Aspergillus in internal associated with invasive pulmonary aspergillosis
1) Confidence 0.32 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.59 Pain Relevance 0
Ten episodes were categorized as proven or probable IPA in this cohort of 48 episodes; within these 10 episodes, Aspergillus DNA was detected in 7 of 10 for the pellet fraction and in only 4 of 10 for the supernatant fraction.
Negative_regulation (detected) of Aspergillus associated with invasive pulmonary aspergillosis
2) Confidence 0.31 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.24 Pain Relevance 0
The presence and growth of Aspergillus on preharvested crops can be reduced through agricultural practices such as proper irrigation and pest management.
Negative_regulation (reduced) of Aspergillus in crops
3) Confidence 0.07 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1764136 Disease Relevance 0.26 Pain Relevance 0

General Comments

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