INT201140

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Context Info
Confidence 0.67
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.31
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Sox2) anatomical structure formation involved in morphogenesis (Sox2) nucleus (Sox2)
DNA binding (Sox2) transcription factor binding (Sox2) cytoplasm (Sox2)
Anatomy Link Frequency
stem 1
Sox2 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 41 78.48 Quite High
Action potential 4 62.88 Quite High
fibrosis 1 13.00 Low Low
Hippocampus 15 5.00 Very Low Very Low Very Low
bDMF 9 5.00 Very Low Very Low Very Low
gABA 8 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
neurotrophin 3 4 5.00 Very Low Very Low Very Low
GABAergic 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 27 99.00 Very High Very High Very High
Hypertrophy 80 96.12 Very High Very High Very High
Recurrence 2 89.72 High High
Cancer 85 89.28 High High
Metastasis 2 84.44 Quite High
Malignant Neoplastic Disease 3 56.80 Quite High
Hypertension 2 46.60 Quite Low
Death 2 39.32 Quite Low
Fibrosis 1 13.00 Low Low
Brain Tumor 1 11.20 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Factors underlying LCC-RyR Coupling Efficiency
Transcription (underlying) of LCC
1) Confidence 0.67 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1764437 Disease Relevance 0.57 Pain Relevance 0.07
CSCs express stem cell-specific transcription factors such as Sox2 as well as other intracellular stem- and progenitor cell markers such as nestin, musashi, or aldehyde dehydrogenase [8].
Transcription (transcription) of Sox2 in stem
2) Confidence 0.47 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3004948 Disease Relevance 0.74 Pain Relevance 0.03
In addition, the cells expressed mRNA of nestin, GFAP, Sox2, Pax6, and vimentin (Fig 2h).
Transcription (expressed) of Sox2
3) Confidence 0.41 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1849968 Disease Relevance 0 Pain Relevance 0
The endogenous mRNA expression of Oct3/4, Sox2, Klf4, c-Myc, p53, p21 and Tert in pGFs, mGFs and TTFs at passages 4 to 6 was determined by real-time RT-PCR analysis.
Transcription (expression) of Sox2
4) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939066 Disease Relevance 0 Pain Relevance 0

General Comments

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