INT201222

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Context Info
Confidence 0.45
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (STX1A) vesicle-mediated transport (STX1A) extracellular region (STX1A)
plasma membrane (STX1A) protein binding, bridging (STX1A) protein complex (STX1A)
Anatomy Link Frequency
lamina 1
STX1A (Homo sapiens)
Pain Link Frequency Relevance Heat
spinothalamic 4 99.96 Very High Very High Very High
burning pain 1 95.88 Very High Very High Very High
Cold hyperalgesia 1 85.92 High High
spinal dorsal horn 1 78.88 Quite High
allodynia 10 77.44 Quite High
c fibre 4 74.88 Quite High
nociceptor 2 68.60 Quite High
Pain 25 57.16 Quite High
Hyperalgesia 1 53.60 Quite High
agonist 2 36.44 Quite Low
Disease Link Frequency Relevance Heat
Pain 23 95.88 Very High Very High Very High
Hyperalgesia 2 85.52 High High
Nociception 5 85.16 High High
Neuropathic Pain 11 77.44 Quite High
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Facial Pain 3 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Even in the presence of menthol it seems 24°C does not provide input of sufficient magnitude to increase HPC STT cell activity beyond cool-sensitive STT cells in lamina I and thus could explain why menthol did not enhance sensitivity to 24°C.
Positive_regulation (increase) of HPC in lamina associated with spinothalamic
1) Confidence 0.45 Published 2006 Journal Mol Pain Section Body Doc Link PMC1764875 Disease Relevance 0.51 Pain Relevance 0.93

General Comments

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