INT201294

Context Info Confidence 0.30 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.60

transport (Grik1, Gabrg1) plasma membrane (Grik1, Gabrg1)

Grik1 (Mus musculus) Gabrg1 (Mus musculus)

Pain Link Frequency Relevance Heat gABA 35 100.00 amygdala 120 97.60 Pyramidal cell 25 91.80 Action potential 3 74.96 Glutamate 3 64.96 Neuronal excitability 5 61.44 antagonist 12 60.36 agonist 4 23.64 GABAergic 17 5.00 Eae 2 5.00

Disease Link Frequency Relevance Heat Anxiety Disorder 50 50.00 Targeted Disruption 6 50.00 Pain 1 5.00 Urological Neuroanatomy 1 5.00 Disseminated Intravascular Coagulation 1 5.00 Ganglion Cysts 1 5.00 Panic Disorder 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Genetic deletion of GluR5 or pharmacological blockade of GluR5 could significantly reduce the tonic GABA current.

Negative_regulation (blockade) of GluR5 Negative_regulation (reduce) of GABA associated with gaba

1) Confidence 0.30 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1766473 Disease Relevance 0 Pain Relevance 0.60

General Comments

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