INT20130

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Context Info
Confidence 0.35
First Reported 1989
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 8
Disease Relevance 4.48
Pain Relevance 1.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Hpd) Golgi apparatus (Hpd) endoplasmic reticulum (Hpd)
cytoplasm (Hpd)
Anatomy Link Frequency
T cell 2
plasma 1
MNP 1
Hpd (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 12 96.20 Very High Very High Very High
cytokine 14 94.40 High High
palliative 11 83.64 Quite High
Potency 3 66.48 Quite High
cINOD 2 57.92 Quite High
Inflammation 5 25.00 Low Low
anesthesia 3 7.68 Low Low
Bile 11 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatitis C Virus Infection 306 100.00 Very High Very High Very High
Cancer 64 99.62 Very High Very High Very High
Infection 54 98.28 Very High Very High Very High
Poisoning 6 96.64 Very High Very High Very High
Viral Infection 18 96.44 Very High Very High Very High
Targeted Disruption 51 96.04 Very High Very High Very High
Immunization 6 89.92 High High
Congenital Anomalies 3 87.68 High High
Metastasis 19 79.12 Quite High
Hepatotoxicity 9 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the LAF activity from lipopolysaccharide (LPS)-treated MNP cultures was increased after Piroxicam (0.1-20 mumol/L) treatment.
Positive_regulation (increased) of LAF in MNP
1) Confidence 0.35 Published 1990 Journal Immunol. Cell Biol. Section Abstract Doc Link 2123471 Disease Relevance 0.06 Pain Relevance 0.33
Since the pioneer report of HPD by Hanyu et al., [16] a large number of patients with UICC stage III GCs was undergoing HPD and five year survival rates from 29% – 87% were reported [17,18].
Positive_regulation (undergoing) of HPD associated with cancer
2) Confidence 0.06 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1885432 Disease Relevance 0.59 Pain Relevance 0.08
The hyporesponsiveness to HCV F protein might reflect a progressive dysfunction of specific T cell responses during the chronic viral infection.
Positive_regulation (hyporesponsiveness) of F protein in T cell associated with viral infection and hepatitis c virus infection
3) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997803 Disease Relevance 1.42 Pain Relevance 0
Interestingly, the three subjects who exhibited F protein specific CD4+ T cell response were all anti-F antibody positive by the ELISA assays.
Positive_regulation (response) of F protein in T cell
4) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997803 Disease Relevance 0.49 Pain Relevance 0.03
In order to identify HCV F protein-specific HTL responses during HCV natural infection, we firstly recruited a cohort of 47 patients with HCV chronic infection and a control group of 22 healthy subjects in our study.
Positive_regulation (identify) of F protein associated with hepatitis c virus infection and infection
5) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997803 Disease Relevance 0.89 Pain Relevance 0
GST exceeded the reference interval in all patients at the time of admission, and F protein was increased in seven.
Positive_regulation (increased) of F protein
6) Confidence 0.04 Published 1989 Journal Clin. Chem. Section Abstract Doc Link 2582614 Disease Relevance 0.38 Pain Relevance 0.34
Subsequent to admission nine, eight, and five patients, respectively, had abnormal concentrations of GST, F protein, and ALT.
Positive_regulation (concentrations) of F protein
7) Confidence 0.03 Published 1989 Journal Clin. Chem. Section Abstract Doc Link 2582614 Disease Relevance 0.42 Pain Relevance 0.32
Concentrations of glutathione S-transferase (GST; glutathione transferase; EC 2.5.1.18) B1 subunits, F protein, and the activity of alanine aminotransferase (ALT; EC 2.6.1.2) were measured in sequential plasma samples taken from nine patients with self-administered paracetamol (acetaminophen) poisoning.
Positive_regulation (Concentrations) of F protein in plasma associated with paracetamol and poisoning
8) Confidence 0.03 Published 1989 Journal Clin. Chem. Section Abstract Doc Link 2582614 Disease Relevance 0.23 Pain Relevance 0.34

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