INT201425

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.20
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
blood 2
IgG (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 42 70.88 Quite High
Arthritis 86 62.80 Quite High
Inflammation 19 57.12 Quite High
Dopamine 38 50.00 Quite Low
Crohn's disease 5 25.88 Quite Low
rheumatoid arthritis 54 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Meningitis 31 92.76 High High
Autoimmune Disease 6 91.44 High High
Systemic Lupus Erythematosus 12 90.72 High High
Targeted Disruption 3 88.08 High High
Systemic Sclerosis 13 82.80 Quite High
Lyme Disease 65 80.12 Quite High
Sepsis 7 77.36 Quite High
Infection 44 70.40 Quite High
Breast Cancer 2 62.16 Quite High
INFLAMMATION 17 57.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BXD2 mice form spontaneous germinal centers which was IL-17-dependent, and treatment with IL-17 promoted the secretion of both IgM and IgG autoantibodies which was reduced by crossing BXD2 mice to IL-17R KO mice [27].
Positive_regulation (promoted) of Localization (secretion) of IgG
1) Confidence 0.08 Published 2010 Journal Semin Immunopathol Section Body Doc Link PMC2836464 Disease Relevance 1.59 Pain Relevance 0.10
RIa, CD64) for which IgG opsonization is not necessary.
Neg (not) Positive_regulation (necessary) of Localization (opsonization) of IgG
2) Confidence 0.04 Published 2010 Journal PLoS Pathogens Section Abstract Doc Link PMC2987830 Disease Relevance 0.40 Pain Relevance 0
Blots were then rinsed and incubated with peroxidase-conjugated anti-mouse IgG (1:4000, Southern Biotech) for ER?
Positive_regulation (incubated) of Localization (peroxidase) of IgG
3) Confidence 0.03 Published 2006 Journal J Mol Signal Section Body Doc Link PMC1769494 Disease Relevance 0.06 Pain Relevance 0
Of the blood samples from the former group of 333 patients, 28 (28/333), namely 8.4%, were found to be positive for the 2-tier IgM and IgG ELISA screen and further confirmed by Western Blot for the detection of antibodies against sonicated whole-cell B. burgdorferi.
Positive_regulation (positive) of Localization (screen) of IgG in blood
4) Confidence 0.02 Published 2010 Journal BMC Res Notes Section Body Doc Link PMC2984391 Disease Relevance 0.14 Pain Relevance 0

General Comments

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