INT201426

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Context Info
Confidence 0.10
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.56
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
filaments 1
IgG (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 38 84.44 Quite High
Kinase C 13 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bullous Skin Disease 304 99.98 Very High Very High Very High
Shock 2 98.28 Very High Very High Very High
Adhesions 51 77.12 Quite High
Acantholysis 65 52.28 Quite High
Volume Depletion And Dehydration 1 37.52 Quite Low
Starvation 2 31.16 Quite Low
Mucocutaneous Lymph Node Syndrome 1 6.76 Low Low
Disease 24 5.00 Very Low Very Low Very Low
Apoptosis 19 5.00 Very Low Very Low Very Low
Blister 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, because p38MAPK-mediated phosphorylation of HSP27 or HSP 25 promoted actin assembly and stabilized F-actin against depolymerization in response to cytochalasin D or heat shock (Benndorf et al. 1994; Geum et al. 2002; Guay et al. 1997), one would expect that PV-IgG-induced HSP27 phosphorylation also would stabilize actin filaments.
Phosphorylation (phosphorylation) of IgG in filaments associated with shock and bullous skin disease
1) Confidence 0.10 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 0.56 Pain Relevance 0
Secondary Ab (either biotinylated mouse IgG or IgM, from Vector Laboratories, Burlingame, CA) was diluted (50 ?
Phosphorylation (biotinylated) of IgG
2) Confidence 0.05 Published 2006 Journal J Mol Signal Section Body Doc Link PMC1769494 Disease Relevance 0 Pain Relevance 0.04

General Comments

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