INT201591

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Context Info
Confidence 0.20
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.18
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Grb2) endosome (Grb2) anatomical structure formation involved in morphogenesis (Grb2)
aging (Grb2) Golgi apparatus (Grb2) nucleus (Grb2)
Anatomy Link Frequency
skin 1
Grb2 (Mus musculus)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 33 33.52 Quite Low
Disease Link Frequency Relevance Heat
Stress 11 100.00 Very High Very High Very High
Hypoxia 2 100.00 Very High Very High Very High
Metastasis 11 63.36 Quite High
Skin Cancer 49 62.92 Quite High
Apoptosis 6 21.72 Low Low
Cancer 9 5.00 Very Low Very Low Very Low
Repression 6 5.00 Very Low Very Low Very Low
Burns 5 5.00 Very Low Very Low Very Low
Hypersensitivity 5 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several other genes involved in the ER/Golgi trafficking or folding of proteins, but not previously reported to be regulated during oxidative stress/hypoxia or the unfolded protein response, were also identified, including Ext1, Ergic3, Grb2, Inpp5e, Man1a2, Prkcsh, Rer1, and Surf4, raising the possibility that these genes may represent new skin stress response genes.
Regulation (regulated) of Grb2 in skin associated with stress and hypoxia
1) Confidence 0.20 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 1.18 Pain Relevance 0

General Comments

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