INT2016

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Context Info
Confidence 0.41
First Reported 1979
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 3.21
Pain Relevance 1.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (MRAP) plasma membrane (MRAP) cytoplasm (MRAP)
Anatomy Link Frequency
chest 1
MRAP (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 4 97.84 Very High Very High Very High
spinal inflammation 12 97.64 Very High Very High Very High
imagery 1 96.24 Very High Very High Very High
Multiple sclerosis 5 93.40 High High
psoriasis 1 93.32 High High
Inflammation 2 86.48 High High
Arthritis 2 84.32 Quite High
Disease Link Frequency Relevance Heat
Seronegative Spondarthritis 8 100.00 Very High Very High Very High
Disease 6 100.00 Very High Very High Very High
Rheumatoid Arthritis 4 97.84 Very High Very High Very High
Low Back Pain 8 97.60 Very High Very High Very High
Syndrome 4 96.56 Very High Very High Very High
Demyelinating Disease 5 93.40 High High
Psoriasis 1 93.32 High High
INFLAMMATION 2 86.48 High High
Rheumatic Diseases 3 83.84 Quite High
Bacterial Infection 1 49.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In ankylosing hyperotosis (Forestier) they prove, based on the findings in 36 patients that in controversial cases the absence of B 27 may be important.
Negative_regulation (absence) of B 27
1) Confidence 0.41 Published 1979 Journal Czech Med Section Abstract Doc Link 316761 Disease Relevance 0.89 Pain Relevance 0.34
Speculative factors which may predispose to apical fibrobullous disease, such as a stiff chest wall, impaired esophageal motiligy, and HL-A antigen B27, were not present in our patient.
Negative_regulation (predispose) of B27 in chest associated with disease
2) Confidence 0.41 Published 1979 Journal Chest Section Abstract Doc Link 436534 Disease Relevance 0.71 Pain Relevance 0.23
Blocking of surface B27 Ag with anti-B27 mAb augmented bacterial invasion in the B27 transfectants.
Negative_regulation (Blocking) of B27
3) Confidence 0.41 Published 1992 Journal J. Immunol. Section Abstract Doc Link 1588045 Disease Relevance 0.08 Pain Relevance 0.04
This is due to the virtual absence of the HLA B27 antigen in the Black population.
Negative_regulation (absence) of B27 associated with seronegative spondarthritis
4) Confidence 0.41 Published 1982 Journal S. Afr. Med. J. Section Abstract Doc Link 7058466 Disease Relevance 0.46 Pain Relevance 0.10
Discrimination of HLA-B27 alleles by group-specific amplification followed by solid-phase sequencing.
Negative_regulation (Discrimination) of B27
5) Confidence 0.05 Published 1996 Journal Hum. Immunol. Section Title Doc Link 8882409 Disease Relevance 0.19 Pain Relevance 0.19
The patient possessed HLA-B27; his complete HLA phenotype was Aw66, B27, Cw2, DR3, and DR5.
Negative_regulation (possessed) of B27
6) Confidence 0.03 Published 1989 Journal Cleve Clin J Med Section Abstract Doc Link 2605779 Disease Relevance 0.87 Pain Relevance 0.70

General Comments

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