INT201602

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.17
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Uvbi1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 7 71.04 Quite High
Inflammatory response 2 42.72 Quite Low
melanocortin 1 receptor 66 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Gastrointestinal Neoplasms 1 88.96 High High
Malignant Neoplastic Disease 4 88.24 High High
Stress 26 84.28 Quite High
Genomic Instability 11 82.44 Quite High
Keratosis 4 80.08 Quite High
Squamous Cell Neoplasms 2 77.60 Quite High
Death 15 74.40 Quite High
Apoptosis 29 71.48 Quite High
INFLAMMATION 9 71.04 Quite High
Dna Damage 5 67.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Collectively, we refer to the 120 UVB × Mc1r genes as the Mc1r-dependent UVB-responsive genes (Table S4) and the 147 UVB × Kit genes as the Kit-dependent UVB-responsive genes (Table S5).
Positive_regulation (dependent) of UVB
1) Confidence 0.04 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 0.05 Pain Relevance 0
Post hoc analyses performed separately on each of the 120 and 147 gene sets yielded three patterns, depending on whether a gene responded to UVB only in the mutant, only in the nonmutant, or in both mutant and nonmutant genotypes (Figure 5).
Spec (whether) Positive_regulation (responded) of UVB
2) Confidence 0.04 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 0.06 Pain Relevance 0
Nicotinamide protected against UV-induced immunosuppression in mice and humans and UV-induced carcinogenesis in mice.
Positive_regulation (induced) of immunosuppression
3) Confidence 0.02 Published 2010 Journal Journal of Nucleic Acids Section Body Doc Link PMC2915624 Disease Relevance 1.06 Pain Relevance 0.04

General Comments

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