INT201608

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.93
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Mc1r) signal transduction (Mc1r) plasma membrane (Mc1r)
signal transducer activity (Mc1r)
Anatomy Link Frequency
Kit 3
Mc1r (Mus musculus)
Uvbi1 (Mus musculus)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 165 73.64 Quite High
Disease Link Frequency Relevance Heat
Cancer 45 90.48 High High
Skin Cancer 245 75.56 Quite High
Repression 30 66.16 Quite High
Stress 55 60.04 Quite High
Stomach Cancer 5 55.12 Quite High
Breast Cancer 5 38.00 Quite Low
Metastasis 55 5.00 Very Low Very Low Very Low
Apoptosis 30 5.00 Very Low Very Low Very Low
Burns 25 5.00 Very Low Very Low Very Low
Hypersensitivity 25 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, Bop1, another negative regulator of the cell cycle, was repressed by UVB in Mc1re/Mc1re animals but not in Mc1r+/Mc1r+ animals, while Mark3 and Cdc2l1, both positive cell cycle regulators, were induced by UVB in Mc1re/Mc1re animals but not in Mc1r+/Mc1r+ animals.
Mc1r Binding (induced) of UVB
1) Confidence 0.03 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 0.36 Pain Relevance 0.07
Similarly, Bop1, another negative regulator of the cell cycle, was repressed by UVB in Mc1re/Mc1re animals but not in Mc1r+/Mc1r+ animals, while Mark3 and Cdc2l1, both positive cell cycle regulators, were induced by UVB in Mc1re/Mc1re animals but not in Mc1r+/Mc1r+ animals.
Mc1r Binding (induced) of UVB
2) Confidence 0.03 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 0.36 Pain Relevance 0.07
We used two-way analysis of variance (ANOVA) to characterize the interaction between genotype and UVB exposure and identified 120 and 147 genes that showed a significant interaction (p = 0.05) between UVB and Mc1r and between UVB and Kit, respectively.
Mc1r Binding (interaction) of UVB in Kit
3) Confidence 0.03 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 0.07 Pain Relevance 0
We used two-way analysis of variance (ANOVA) to characterize the interaction between genotype and UVB exposure and identified 120 and 147 genes that showed a significant interaction (p = 0.05) between UVB and Mc1r and between UVB and Kit, respectively.
Mc1r Binding (interaction) of UVB in Kit
4) Confidence 0.03 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 0.07 Pain Relevance 0
We used two-way analysis of variance (ANOVA) to characterize the interaction between genotype and UVB exposure and identified 120 and 147 genes that showed a significant interaction (p = 0.05) between UVB and Mc1r and between UVB and Kit, respectively.
Mc1r Binding (interaction) of UVB in Kit
5) Confidence 0.03 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 0.07 Pain Relevance 0

General Comments

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