INT201611

Context Info Confidence 0.03 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.30 Pain Relevance 0.08

cell proliferation (Bop1) nucleolus (Bop1) nucleus (Bop1) ribosome biogenesis (Bop1)

Uvbi1 (Mus musculus) Bop1 (Mus musculus)

Pain Link Frequency Relevance Heat melanocortin 1 receptor 33 81.40

Disease Link Frequency Relevance Heat Skin Cancer 49 83.32 Cancer 9 76.00 Stress 11 67.80 Stomach Cancer 1 40.64 Breast Cancer 1 23.52 Metastasis 11 5.00 Repression 6 5.00 Apoptosis 6 5.00 Burns 5 5.00 Hypersensitivity 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Similarly, Bop1, another negative regulator of the cell cycle, was repressed by UVB in Mc1re/Mc1re animals but not in Mc1r+/Mc1r+ animals, while Mark3 and Cdc2l1, both positive cell cycle regulators, were induced by UVB in Mc1re/Mc1re animals but not in Mc1r+/Mc1r+ animals.

UVB Negative_regulation (repressed) of Bop1

1) Confidence 0.03 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 0.30 Pain Relevance 0.08

General Comments

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