INT201614

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 2
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.42
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Mc1r) signal transduction (Mc1r) plasma membrane (Mc1r)
signal transducer activity (Mc1r)
Anatomy Link Frequency
melanocytes 1
keratinocytes 1
Mc1r (Mus musculus)
Uvbi1 (Mus musculus)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 66 85.84 High High
Disease Link Frequency Relevance Heat
Skin Cancer 98 93.16 High High
Melanoma 4 87.84 High High
Death 4 85.20 High High
Apoptosis 12 74.24 Quite High
Cancer 18 71.48 Quite High
Metastasis 22 5.00 Very Low Very Low Very Low
Stress 22 5.00 Very Low Very Low Very Low
Repression 12 5.00 Very Low Very Low Very Low
Burns 10 5.00 Very Low Very Low Very Low
Hypersensitivity 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The nature of our experimental system—an integrated tissue collected from whole animals—makes it difficult to assess whether Mc1r signaling might affect UVB-induced cell cycle arrest in keratinocytes, melanocytes, or both.
Mc1r Spec (might) Regulation (affect) of UVB in melanocytes
1) Confidence 0.04 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 0.71 Pain Relevance 0.49
The nature of our experimental system—an integrated tissue collected from whole animals—makes it difficult to assess whether Mc1r signaling might affect UVB-induced cell cycle arrest in keratinocytes, melanocytes, or both.
Mc1r Spec (might) Regulation (affect) of UVB in keratinocytes
2) Confidence 0.01 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1774588 Disease Relevance 0.71 Pain Relevance 0.49

General Comments

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