INT20162

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Context Info
Confidence 0.02
First Reported 1990
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.07
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crh, GNRH1) extracellular region (Crh, GNRH1) signal transduction (GNRH1)
cell-cell signaling (GNRH1) response to stress (Crh) cytoplasm (Crh)
Anatomy Link Frequency
neuronal 1
Crh (Rattus norvegicus)
GNRH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
monoamine 5 98.20 Very High Very High Very High
narcan 5 91.92 High High
antagonist 5 91.40 High High
opiate 2 71.12 Quite High
Serotonin 1 62.12 Quite High
noradrenaline 1 61.56 Quite High
Dopamine 1 60.96 Quite High
Endogenous opioid 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Stress 1 73.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of corticotropin-releasing factor (CRF) on the hypothalamic gonadotropin-releasing hormone (GnRH) pulse generator, the central neuronal system governing pulsatile pituitary luteinizing hormone (LH) secretion, was studied electro-physiologically in 6 ovariectomized rhesus monkeys bearing bilateral arrays of recording electrodes implanted in the mediobasal hypothalamus.
CRF Regulation (effect) of gonadotropin-releasing hormone in neuronal
1) Confidence 0.02 Published 1990 Journal Neuroendocrinology Section Abstract Doc Link 2125701 Disease Relevance 0 Pain Relevance 0
It has been suggested that the responses in monoaminergic system activity are highly dependent upon the physiological state of the animal and that beta-endorphin and corticoliberin may indirectly modulate LHRH and other hypothalamic hormone secretion by monoaminergic systems.
corticoliberin Regulation (modulate) of LHRH associated with monoamine
2) Confidence 0.00 Published 1996 Journal Acta Neurobiol Exp (Wars) Section Abstract Doc Link 8917909 Disease Relevance 0.07 Pain Relevance 0.62

General Comments

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