INT201637

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Context Info
Confidence 0.23
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.99
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Bad) cell proliferation (Bad) cytosol (Bad)
mitochondrion (Bad) cytoplasm (Bad)
Bad (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 11 92.80 High High
imagery 33 79.24 Quite High
antagonist 4 51.04 Quite High
Inflammation 14 5.00 Very Low Very Low Very Low
Hippocampus 7 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
Eae 6 5.00 Very Low Very Low Very Low
long-term potentiation 5 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 171 100.00 Very High Very High Very High
Sprains And Strains 6 98.60 Very High Very High Very High
Breast Cancer 1 95.12 Very High Very High Very High
Toxicity 15 93.60 High High
Diabetes Mellitus 30 92.28 High High
Cancer 29 92.00 High High
Shock 4 88.20 High High
Death 59 81.52 Quite High
Autoimmune Disease 1 80.12 Quite High
Necrosis 3 79.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Until the effects of BAD on proliferation are dissected on a molecular level, we remain with the notion that effects of BAD expression on proliferation are cell type-dependent.


Regulation (effects) of Gene_expression (expression) of BAD
1) Confidence 0.23 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2704953 Disease Relevance 0.68 Pain Relevance 0.03
In cells isolated from matrigel, HF diet down-regulated expression of pro-apoptotic Bcl-2 family members: Bak1, Bad, and Bcl2L11.
Regulation (regulated) of Gene_expression (expression) of Bad associated with apoptosis
2) Confidence 0.21 Published 2009 Journal Lipids Health Dis Section Body Doc Link PMC2674043 Disease Relevance 0.49 Pain Relevance 0
The Bcl-2 family includes pro-apoptotic (Bax and Bad) and anti-apoptotic (Bcl-2 and Bcl-XL) proteins, whose expression and activity is regulated through different signaling pathways including trophic factors deprivation, A?
Regulation (regulated) of Gene_expression (expression) of Bad associated with apoptosis
3) Confidence 0.04 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1775042 Disease Relevance 1.34 Pain Relevance 0.05
In conjunction with the availability of mice expressing GFP under the insulin promoter in both B6 and NOD background and strains expressing red or far-red fluorophores controlled by a variety of promoters, we believe there is ample opportunity to translate our approach to other diabetes models.
Regulation (under) of Gene_expression (expressing) of insulin promoter associated with diabetes mellitus and sprains and strains
4) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3009738 Disease Relevance 0.48 Pain Relevance 0.10

General Comments

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