INT201740

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ngf, Nfkb1) mitochondrion (Nfkb1) DNA binding (Nfkb1)
protein complex (Nfkb1) cytoplasm (Nfkb1) cytosol (Nfkb1)
Anatomy Link Frequency
neuronal 2
Ngf (Mus musculus)
Nfkb1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 8 99.36 Very High Very High Very High
Central nervous system 4 97.00 Very High Very High Very High
Inflammatory mediators 2 92.28 High High
Inflammation 9 86.20 High High
chemokine 1 74.88 Quite High
cINOD 1 34.16 Quite Low
cOX1 1 25.84 Quite Low
Glutamate 2 7.04 Low Low
Hippocampus 7 5.00 Very Low Very Low Very Low
Eae 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 7 97.28 Very High Very High Very High
Apoptosis 133 92.16 High High
INFLAMMATION 13 91.88 High High
Disease 127 78.48 Quite High
Cognitive Disorder 16 63.28 Quite High
Retinoblastoma 1 43.84 Quite Low
Aging 5 34.36 Quite Low
Stress 32 32.92 Quite Low
Carcinoma 1 20.12 Low Low
Toxicity 15 6.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NGF-mediated activation of both TrkA and p75, the latter being increased following brain damage, may promote neuronal survival through activation of NF-kB [182], which can also be directly induced by most of the cytokines.
Positive_regulation (induced) of NGF Positive_regulation (activation) of NF-kB in neuronal associated with cytokine
1) Confidence 0.01 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1775042 Disease Relevance 1.07 Pain Relevance 0.51

General Comments

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