INT201742

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ngfr, Gtf3a) nuclear envelope (Ngfr) Golgi apparatus (Ngfr)
intracellular (Gtf3a) DNA binding (Gtf3a) cytoplasm (Ngfr)
Anatomy Link Frequency
SC-1 1
Ngfr (Mus musculus)
Gtf3a (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 5 16.24 Low Low
Inflammation 9 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Hippocampus 7 5.00 Very Low Very Low Very Low
Eae 6 5.00 Very Low Very Low Very Low
long-term potentiation 5 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 56 98.04 Very High Very High Very High
Apoptosis 133 96.72 Very High Very High Very High
Disease 127 50.00 Quite Low
Neurodegenerative Disease 36 5.00 Very Low Very Low Very Low
Stress 32 5.00 Very Low Very Low Very Low
Cognitive Disorder 16 5.00 Very Low Very Low Very Low
Toxicity 15 5.00 Very Low Very Low Very Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Parkinson's Disease 8 5.00 Very Low Very Low Very Low
Injury 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several adaptor proteins have been found to interact with the DD of p75, including: NRIF1/2 (Neurotrophin-Receptor Interacting Factor 1 and 2) and NADE (Neurotrophin-Associated cell Death Executor) both involved in apoptosis; SC-1 (Schwann cell-1) and NRAGE (Neurotrophin Receptor-interacting MAGE homologue) that are associated to growth arrest and cell cycle events; RIP2 (Receptor-Interacting Protein 2), which possesses a CARD (Caspase Recruitment Domain) and TRAF-4/6 (TNF Receptor Associated Factor-4 and -6), both linked to survival responses [159-161].
p75 Binding (interact) of Factor in SC-1 associated with apoptosis and death
1) Confidence 0.00 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1775042 Disease Relevance 0.77 Pain Relevance 0

General Comments

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