INT201744

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (App) extracellular matrix organization (App) DNA binding (App)
cytoplasm (App) extracellular space (Ngf) signal transduction (Ngf)
Ngf (Mus musculus)
App (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 5 80.32 Quite High
Kinase C 5 57.60 Quite High
Hippocampus 7 56.24 Quite High
Inflammation 9 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Eae 6 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 127 85.64 High High
Cognitive Disorder 16 85.40 High High
Aging 5 80.88 Quite High
Apoptosis 133 78.84 Quite High
Targeted Disruption 3 60.68 Quite High
Death 56 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 36 5.00 Very Low Very Low Very Low
Stress 32 5.00 Very Low Very Low Very Low
Toxicity 15 5.00 Very Low Very Low Very Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In PC12 cells, APP transcription and secretion have been found to be regulated by NGF and its receptors TrkA and p75: TrkA activation increases APP processing and secretion, while p75 signaling increases APP transcription [117].
NGF Regulation (regulated) of Transcription (transcription) of APP
1) Confidence 0.06 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1775042 Disease Relevance 0.39 Pain Relevance 0.15

General Comments

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