INT201765

Context Info Confidence 0.00 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.28 Pain Relevance 0

mitochondrion (BCL2L1, Bax) intracellular (BCL2L1, Bax) cytoplasm (BCL2L1, Bax) cytosol (BCL2L1, Bax) nucleus (BCL2L1, Bax) endoplasmic reticulum (Bax)

BCL2L1 (Homo sapiens) Bax (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 9 5.00 cytokine 8 5.00 Hippocampus 7 5.00 Eae 6 5.00 long-term potentiation 5 5.00 Kinase C 5 5.00 Neurotransmitter 5 5.00 Central nervous system 4 5.00 Neuropeptide 2 5.00 Inflammatory mediators 2 5.00

Disease Link Frequency Relevance Heat Apoptosis 133 85.56 Coronary Artery Disease 1 55.84 Disease 127 50.00 Death 56 38.44 Stress 32 36.36 Neurodegenerative Disease 36 5.00 Cognitive Disorder 16 5.00 Toxicity 15 5.00 INFLAMMATION 13 5.00 Parkinson's Disease 8 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In viable cells, Bcl-XL binds Bax and Bak, thus keeping them in an inactive form.

Bcl-XL Binding (binds) of Bax

1) Confidence 0.00 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1775042 Disease Relevance 0.28 Pain Relevance 0

General Comments

This test has worked.