INT201779

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.91
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mtpn) nucleus (Mtpn) cytoplasm (Mtpn)
Anatomy Link Frequency
Fibroblast 1
Mtpn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Eae 6 32.64 Quite Low
Inflammation 9 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Hippocampus 7 5.00 Very Low Very Low Very Low
long-term potentiation 5 5.00 Very Low Very Low Very Low
Kinase C 5 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 127 94.08 High High
Apoptosis 135 84.96 Quite High
Stress 39 79.56 Quite High
Aging 5 77.64 Quite High
Death 57 72.96 Quite High
Toxicity 15 70.48 Quite High
Diabetes Mellitus 40 52.28 Quite High
Increased Venous Pressure Under Development 1 45.60 Quite Low
Hyperlipidemia 1 33.72 Quite Low
Disorder Of Lipid Metabolism 1 28.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of PI 3-kinase has been shown to be necessary and sufficient for growth factor–induced increase in Akt phosphorylation (38).
Phosphorylation (phosphorylation) of growth factor
1) Confidence 0.01 Published 2008 Journal Diabetes Section Body Doc Link PMC2551671 Disease Relevance 0 Pain Relevance 0
is phosphorylated (and inactivated) through a PI3K/Akt signaling pathway induced by IGF-1, NGF and any growth factor whose activity is mediated by receptors with intrinsic tyrosine kinase activity [201], including also Fibroblast Growth Factor-2 (FGF-2).
Phosphorylation (phosphorylated) of growth factor in Fibroblast
2) Confidence 0.01 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1775042 Disease Relevance 0.91 Pain Relevance 0

General Comments

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