INT201810

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.56
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.94
Pain Relevance 1.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (LEFTY2) extracellular region (LEFTY2)
Anatomy Link Frequency
macrophages 1
osteoblasts 1
skeletal muscle 1
LEFTY2 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 87 99.80 Very High Very High Very High
Inflammatory mediators 6 99.76 Very High Very High Very High
fibrosis 60 99.20 Very High Very High Very High
cytokine 61 98.20 Very High Very High Very High
Antinociceptive 3 94.72 High High
Osteoarthritis 40 93.20 High High
Arthritis 30 92.96 High High
Inflammation 128 92.72 High High
Analgesic 3 77.28 Quite High
cINOD 6 74.96 Quite High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 87 99.80 Very High Very High Very High
INFLAMMATION 140 99.36 Very High Very High Very High
Pulmonary Fibrosis 41 99.20 Very High Very High Very High
Arthritis 23 93.88 High High
Osteoarthritis 40 93.20 High High
Experimental Arthritis 13 92.96 High High
Hemorrhage 3 90.76 High High
Fibrosis 42 86.80 High High
Cancer 16 78.96 Quite High
Chronic Disease 2 76.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EBAF stimulates expression proMMP-3 and -7 in proliferative phase human endometrial explants, and P inhibits this as well as inhibition of EBAF expression [46].
Gene_expression (expression) of EBAF
1) Confidence 0.56 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1775064 Disease Relevance 0.09 Pain Relevance 0.03
express different transforming growth factor-beta (TGF-?)
Gene_expression (express) of transforming growth factor-beta
2) Confidence 0.15 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246244 Disease Relevance 1.14 Pain Relevance 0.44
The levels of alkaline phosphatase, osteocalcin, type I collagen, interleukin (IL)-6, transforming growth factor-beta, prostaglandin E2 (PGE2), leukotriene B4, and proteases, including urokinase, cathepsin K, and the metalloprotease (MMP)-13, have all been found to be elevated in human OA subchondral bone osteoblasts [6,9-13].
Gene_expression (levels) of transforming growth factor-beta in osteoblasts associated with osteoarthritis
3) Confidence 0.07 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2483463 Disease Relevance 1.09 Pain Relevance 0.59
Moreover, this latex also increased NO and TNF-alpha and decreased transforming growth factor-beta (TGF-beta) production in macrophages.
Gene_expression (production) of transforming growth factor-beta in macrophages
4) Confidence 0.05 Published 2010 Journal J Inflamm (Lond) Section Body Doc Link PMC3019217 Disease Relevance 0.46 Pain Relevance 0.21
PF was induced in rats by adenoviral gene transfer of transforming growth factor-beta.
Gene_expression (transfer) of transforming growth factor-beta associated with fibrosis
5) Confidence 0.03 Published 2008 Journal J Transl Med Section Abstract Doc Link PMC2365932 Disease Relevance 1.09 Pain Relevance 0.47
In general, studies that have compared the expression of MRFs such as myogenic determination factor (myoD), myogenic regulatory factor 5, and myogenin in rats have found that expression of these factors is decreased in older compared to younger skeletal muscle [51].
Gene_expression (expression) of myogenic determination factor in skeletal muscle
6) Confidence 0.02 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2832869 Disease Relevance 0.06 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox