INT201845

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Context Info
Confidence 0.50
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.04
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CYR61) extracellular region (CYR61) extracellular matrix organization (CYR61)
Anatomy Link Frequency
endometrium 2
CYR61 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 184 99.72 Very High Very High Very High
cytokine 10 96.40 Very High Very High Very High
metalloproteinase 24 34.72 Quite Low
Etanercept 2 13.04 Low Low
Inflammation 14 5.00 Very Low Very Low Very Low
pain pelvic 4 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis 262 99.72 Very High Very High Very High
Disease 98 87.32 High High
Reprotox - General 3 26 5.00 Very Low Very Low Very Low
INFLAMMATION 16 5.00 Very Low Very Low Very Low
Apoptosis 14 5.00 Very Low Very Low Very Low
Repression 4 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of CYR61 mRNA is rapidly induced in an immediate early response manner by a spectrum of stimuli including growth factors, cytokines and estrogens [58-60].
Positive_regulation (induced) of Transcription (Expression) of CYR61 associated with cytokine
1) Confidence 0.50 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1775067 Disease Relevance 0.60 Pain Relevance 0.20
CYR61 mRNA and protein levels were increased in a time dependent manner in the eutopic endometrium, during the window of receptivity, of baboons experimentally induced with endometriosis [56].
Positive_regulation (increased) of Transcription (levels) of CYR61 in endometrium associated with endometriosis
2) Confidence 0.34 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1775067 Disease Relevance 0.44 Pain Relevance 0.12

General Comments

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