INT201865

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PGR, NCOA1) enzyme binding (PGR, NCOA1) DNA binding (PGR, NCOA1)
nucleus (PGR, NCOA1) small molecule metabolic process (NCOA1) transferase activity, transferring acyl groups (NCOA1)
PGR (Homo sapiens)
NCOA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 16 97.64 Very High Very High Very High
antagonist 28 75.04 Quite High
endometriosis 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Uterine Fibroids 21 41.04 Quite Low
Apoptosis 4 36.08 Quite Low
Uterine Hemorrhage 2 14.00 Low Low
Reprotox - General 1 11 5.00 Very Low Very Low Very Low
Endometriosis (extended) 9 5.00 Very Low Very Low Very Low
Hemorrhage 8 5.00 Very Low Very Low Very Low
Hyperplasia 4 5.00 Very Low Very Low Very Low
Gynecological Disease 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More recent molecular studies show that asoprisnil-liganded PR promotes the recruitment of the coactivator SRC-1 in an in vitro model [53] which could explain the partial agonist effects observed in animal models and humans.
PR Binding (recruitment) of SRC-1 associated with agonist
1) Confidence 0.03 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1775068 Disease Relevance 0 Pain Relevance 0.17

General Comments

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