INT201925

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Context Info
Confidence 0.45
First Reported 2006
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CD22) plasma membrane (CD22)
Anatomy Link Frequency
plasma cells 2
CD22 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 6 8.16 Low Low
Paresthesia 4 5.00 Very Low Very Low Very Low
visual analogue scale 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
carpal tunnel syndrome 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 10 84.24 Quite High
Disease 32 78.60 Quite High
Serum Sickness 8 78.04 Quite High
Lymphatic System Cancer 20 76.72 Quite High
Autoimmune Disease 16 70.28 Quite High
Increased Venous Pressure Under Development 2 15.92 Low Low
Dyspnea 2 15.12 Low Low
Vomiting 4 14.40 Low Low
Pressure And Volume Under Development 2 11.92 Low Low
Pain 6 8.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CD22 is expressed at low levels on immature B cells, expressed at higher levels on mature IgM+, IgD+ B cells, and absent on differentiated plasma cells.
Positive_regulation (levels) of Neg (absent) Gene_expression (expressed) of CD22 in plasma cells
1) Confidence 0.45 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779377 Disease Relevance 0.49 Pain Relevance 0
At the final evaluation, all the patients recovered to the same increased CD22 expression compared with normal, as observed in patients with untreated pSS.


Positive_regulation (increased) of Gene_expression (expression) of CD22
2) Confidence 0.42 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779377 Disease Relevance 0.08 Pain Relevance 0

General Comments

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