INT201942

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Context Info
Confidence 0.33
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.90
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (DPP4, CXCL10) Golgi apparatus (DPP4) endoplasmic reticulum (DPP4)
cell-cell signaling (CXCL10) peptidase activity (DPP4) extracellular space (CXCL10)
Anatomy Link Frequency
lymphocytes 1
natural killer cells 1
DPP4 (Homo sapiens)
CXCL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 58 94.84 High High
Inflammation 28 78.80 Quite High
cytokine 52 73.76 Quite High
Arthritis 88 61.76 Quite High
antagonist 4 58.24 Quite High
rheumatoid arthritis 44 57.64 Quite High
spinal inflammation 38 56.96 Quite High
Inflammatory mediators 4 49.84 Quite Low
psoriasis 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 30 78.80 Quite High
Arthritis 54 68.32 Quite High
Rheumatoid Arthritis 44 57.64 Quite High
Low Back Pain 38 56.96 Quite High
Disease 2 48.76 Quite Low
Arthropathy 6 44.12 Quite Low
Seronegative Spondarthritis 34 38.76 Quite Low
Autoimmune Disease 2 18.64 Low Low
Necrosis 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, CD26 is coexpressed with CXCR3 on the infiltrating Th1 lymphocytes and natural killer cells, and rapidly inactivates CXCL10 by NH2-terminal processing [22,44].
CD26 Negative_regulation (inactivates) of CXCL10 in natural killer cells
1) Confidence 0.33 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779382 Disease Relevance 0.45 Pain Relevance 0.65
In addition, CD26 is coexpressed with CXCR3 on the infiltrating Th1 lymphocytes and natural killer cells, and rapidly inactivates CXCL10 by NH2-terminal processing [22,44].
CD26 Negative_regulation (inactivates) of CXCL10 in lymphocytes
2) Confidence 0.11 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779382 Disease Relevance 0.45 Pain Relevance 0.65

General Comments

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