INT201943

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Context Info
Confidence 0.20
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (DPP4, CXCL10) Golgi apparatus (DPP4) endoplasmic reticulum (DPP4)
cell-cell signaling (CXCL10) peptidase activity (DPP4) extracellular space (CXCL10)
Anatomy Link Frequency
Leukocyte 1
mesenchymal cells 1
DPP4 (Homo sapiens)
CXCL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 26 100.00 Very High Very High Very High
Inflammation 14 100.00 Very High Very High Very High
chemokine 29 97.64 Very High Very High Very High
Arthritis 44 48.88 Quite Low
spinal inflammation 19 44.28 Quite Low
rheumatoid arthritis 22 42.36 Quite Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 15 100.00 Very High Very High Very High
Arthropathy 3 100.00 Very High Very High Very High
Cancer 3 91.52 High High
Necrosis 3 91.24 High High
Arthritis 27 48.88 Quite Low
Low Back Pain 19 44.28 Quite Low
Seronegative Spondarthritis 17 43.32 Quite Low
Rheumatoid Arthritis 22 42.36 Quite Low
Starvation 2 5.00 Very Low Very Low Very Low
Rheumatic Diseases 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathies

Leukocyte infiltration during acute and chronic inflammation is regulated by exogenous and endogenous factors, including cytokines, chemokines and proteases.

Regulation (regulated) of CD26 in Leukocyte Binding (interaction) of CXCL10 in mesenchymal cells associated with chemokine, inflammation, arthropathy and cytokine
1) Confidence 0.20 Published 2006 Journal Arthritis Res Ther Section Title Doc Link PMC1779382 Disease Relevance 0.58 Pain Relevance 0.42

General Comments

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